208671

Bis(triphenylphosphine)palladium(II) dichloride

98%

• 동의어(들): Dichlorobis(triphenylphosphine)palladium(II), Palladium(II)bis(triphenylphosphine) dichloride, PdCl₂(PPh₃)₂
• Linear Formula: [(C₆H₅)₃P]₂PdCl₂
• CAS Number: 13965-03-2
• Molecular Weight: 701.90
• Beilstein: 4935975
• EC Number: 237-744-2
• MDL number: MFCD00009593
• UNSPSC 코드: 12161600
• PubChem Substance ID: 24852524
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 98%
• 양식: solid
• 반응 적합성: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst
• SMILES string: Cl[Pd]Cl.c1(P(c2ccccc2)c3ccccc3)ccccc1.c4(P(c5ccccc5)c6ccccc6)ccccc4
• InChI: 1S/2C18H15P.2ClH.Pd/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;;;/h2*1-15H;2*1H;/q;;;;+2/p-2
• InChI key: YNHIGQDRGKUECZ-UHFFFAOYSA-L

설명

일반 설명

Bis(triphenylphosphine)palladium(II) dichloride ((PdCl₂(PPh₃)₂) is an organopalladium complex containing tertiary phosphine ligands that is commonly used in C-C bond forming reactions such as Heck arylation, Suzuki coupling, Stille coupling, and Sonogashira coupling.

애플리케이션

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Bis(triphenylphosphine)palladium(II) dichloride can be used as a catalyst in the:

• Coupling of 2-iodoanisole and terminal alkynes to synthesize 2,3-disubstituted benzofurans.
• Copper-free Sonogashira cross-coupling reaction to synthesize diphenylacetylene.
• Regioselective hydrocarboxylation of styrene.
• Negishi coupling of fluoroarylzinc pivalates to prepare fluorinated oligophenyls.
• Coupling of iodo-α-β-unsaturated esters to afford tetrasubstituted olefins.

For small scale and high throughput uses, product is also available as ChemBeads (927759)

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317,H413
• 예방조치 성명서: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 4 - Skin Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)