195529

Iodotrimethylsilane

97%

• 동의어(들): TMIS, Trimethyliodosilane
• Linear Formula: (CH₃)₃SiI
• CAS Number: 16029-98-4
• Molecular Weight: 200.09
• Beilstein: 1731136
• EC Number: 240-171-0
• MDL number: MFCD00001028
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24851696
• NACRES: NA.22

속성

• Quality Level: 300
• 분석: 97%
• 양식: liquid
• 포함: copper as stabilizer
• refractive index: n20/D 1.471 (lit.)
• bp: 106 °C (lit.)
• density: 1.406 g/mL at 25 °C (lit.)
• 저장 온도: −20°C
• SMILES string: C[Si](C)(C)I
• InChI: 1S/C3H9ISi/c1-5(2,3)4/h1-3H3
• InChI key: CSRZQMIRAZTJOY-UHFFFAOYSA-N

설명

일반 설명

Iodotrimethylsilane is a multipurpose reagent used in various organic reactions. It is used for the dealkylation of few compounds like lactones, ethers, acetals, and carbamates and trimethylsilylating agent for the synthesis of silyl imino esters, alkyl and alkenyl silanes, etc. It also acts as a Lewis acid catalyst and as a reducing agent in many organic reactions.[1][1]

[1]Iodotrimethylsilane is a hard-soft reagent that reacts readily with organic compounds containing oxygen (a hard base) forming a strong siliconoxygen bond.[2]

애플리케이션

Efficient reagent for cleaving ethers, esters, carbamates, ketals, and lactones.[3]

For the introduction of the TMS group, e.g., TMS enol ethers.[4] Key reagent for the selective deprotection of an N-Cbz group in the presence of a trimethyltin moiety.[5]

Reagent was recently reported to convert allyl- and benzylphosphotriesters to the corresponding iodides.[6]

안전성 정보

• 픽토그램: GHS02,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H225,H314
• 예방조치 성명서: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• 보충제 위험성: EUH014
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): -23.8 °F - closed cup
• Flash Point (°C): -31 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter