137030
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate
99%
동의어(들):
3,5-Dicarbethoxy-1,4-dihydrocollidine, DDC
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모든 사진(1)
크기 선택
보기 변경
25 G
₩149,611
About This Item
실험식(Hill 표기법):
C14H21NO4
CAS Number:
Molecular Weight:
267.32
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Quality Level
분석
99%
양식
powder
mp
130-132 °C (lit.)
SMILES string
CCOC(=O)C1=C(C)NC(C)=C(C1C)C(=O)OCC
InChI
1S/C14H21NO4/c1-6-18-13(16)11-8(3)12(14(17)19-7-2)10(5)15-9(11)4/h8,15H,6-7H2,1-5H3
InChI key
CDVAIHNNWWJFJW-UHFFFAOYSA-N
애플리케이션
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate was used to induce Mallory-Denk body formation in mice in vivo[1].
생화학적/생리학적 작용
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate blocks the heme synthesis and prevents the induction of hepatic heme oxygenase-1 in mice[2].
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Tohru Itoh et al.
FEBS letters, 583(4), 777-781 (2009-01-29)
In injured livers where hepatocyte growth is severely limited, facultative hepatic stem/progenitor cells, termed oval cells in rodents, are known to emerge and contribute to the regeneration process. Here, we investigated a possible involvement of Wnt signaling during mouse oval
Pavel Strnad et al.
Hepatology (Baltimore, Md.), 48(3), 931-942 (2008-08-13)
The cytoplasmic hepatocyte inclusions, Mallory-Denk bodies (MDBs), are characteristic of several liver disorders, including alcoholic and nonalcoholic steatohepatitis. In mice, MDBs can be induced by long-term feeding with 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) for 3 to 4 months or rapidly reformed in DDC-induced
Volker Mostert et al.
Drug metabolism reviews, 39(2-3), 619-626 (2007-09-06)
Heme oxygenase (HO)-1 is induced by oxidative stress and protects against oxidant injury. We examined the effect of rapid induction of hepatic HO-1 on serum iron level. Serum iron was approximately doubled within 6 h when HO-1 was induced by
Leila Jemail et al.
Scientific reports, 8(1), 6415-6415 (2018-04-25)
Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown. We aimed to investigate the precise roles of KCs in
Yuya Terashima et al.
Nature communications, 11(1), 609-609 (2020-02-01)
Tumor-associated macrophages affect tumor progression and resistance to immune checkpoint therapy. Here, we identify the chemokine signal regulator FROUNT as a target to control tumor-associated macrophages. The low level FROUNT expression in patients with cancer correlates with better clinical outcomes.
활성 필터
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