10919

Fmoc isothiocyanate

≥98.0% (CHN)

• 동의어(들): 9-Fluorenylmethoxycarbonyl isothiocyanate, 9-Fluorenylmethyl isothiocyanatoformate
• 실험식(Hill 표기법): C₁₆H₁₁NO₂S
• CAS Number: 199915-38-3
• Molecular Weight: 281.33
• Beilstein: 7930648
• MDL number: MFCD01861169
• UNSPSC 코드: 12352005
• PubChem Substance ID: 57646854
• NACRES: NA.22

속성

• 분석: ≥85% (coupling to amines); ≥98.0% (CHN)
• solubility: ethanol: soluble
• 형광: λ_ex 264 nm; λ_em 313 nm
• 응용 분야: peptide synthesis
• 작용기: Fmoc; amine; isothiocyanate
• 저장 온도: −20°C
• SMILES string: O=C(OCC1c2ccccc2-c3ccccc13)N=C=S
• InChI: 1S/C16H11NO2S/c18-16(17-10-20)19-9-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9H2
• InChI key: DHMYULZVFHHEHE-UHFFFAOYSA-N

설명

애플리케이션

Fmoc isothiocyanate can be used:

• As a starting material in the preparation of biologically relevant pharmacophores named N-aryl-N′-carboalkoxy guanidines.[1]
• In one of the intermediate steps for the synthesis of N-aryl-N-thiazolyl derivatives.[2]
• To synthesize cyclic isothiourea derivatives as potent neuropeptide Y (NPY) Y1 receptor antagonists.[3]
• To prepare 2-aminothiazoles,[4] aminobenz-imidazole conjugated thiazoles,[5] and thiazole derived cyclopeptides[6].

기타 정보

Reagent for the synthesis of substituted thioureas from amines[7]

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H318,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves