106224

3-Bromothiophene

97%

• 동의어(들): 3-Thienyl bromide
• 실험식(Hill 표기법): C₄H₃BrS
• CAS Number: 872-31-1
• Molecular Weight: 163.04
• Beilstein: 105338
• EC Number: 212-821-3
• MDL number: MFCD00005464
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24846726
• NACRES: NA.22

속성

• 분석: 97%
• refractive index: n20/D 1.591 (lit.)
• bp: 150 °C (lit.)
• density: 1.74 g/mL at 25 °C (lit.)
• 작용기: bromo
• SMILES string: Brc1ccsc1
• InChI: 1S/C4H3BrS/c5-4-1-2-6-3-4/h1-3H
• InChI key: XCMISAPCWHTVNG-UHFFFAOYSA-N

설명

애플리케이션

3-Bromothiophene can be used as a reactant to synthesize:

• 3,3-Bithiophene via borylation followed by Suzuki coupling.[1]
• 3-Alkylthiophenes by NiDPPP⁺⁺ catalyzed cross-coupling with Grignard reagents.[2]
• 3-Lithiothiophene by treating with n-butyllithium in hexane.[3]
• Derivatives of thienylenic α, ω−diformyl−α−oligothiophenes[4].
• N-(2-(3-bromothiophen-2-yl)phenyl)methanesulfonamides by coupling at the 2-position with N-arylmethanesulfonamides, mediated by iodobenzene diacetate (178721).[5]

안전성 정보

• 픽토그램: GHS02,GHS06,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H226,H301,H310 + H330,H317,H319,H335,H411
• 예방조치 성명서: P210 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 125.6 °F - closed cup
• Flash Point (°C): 52 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter