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Merck

PRKACA

protein kinase, cAMP-dependent, catalytic, alpha

동의어:
PKACA
:
UniProtKB ID:
Clone ID:
  • Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
  • Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
  • naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
  • sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
  • domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
  • dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
  • Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
  • cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
  • domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-PKA α/β CAT (pThr197) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
immunohistochemistry
western blot
Anti-PRKACA (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
응용분야
immunohistochemistry
western blot
ANTI-PKA C-ALPHA/PKA C-BETA(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
immunohistochemistry
western blot
Anti-PRKACA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-PKA α antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Protein Kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt, ≥90% (HPLC), lyophilized powder,
mouse, rat, human
Tyrphostin A9, solid,
mouse, human
Adenine, BioReagent, suitable for cell culture,
human, rat, mouse
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
human, rat, mouse
Adenine, ≥99%,
human, rat, mouse

Proteins

제품 번호
설명
PKA Protein, Recombinant, 10 µg, Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.,
Protein Kinase A catalytic subunit human, >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution,
human
Protein Kinase A from bovine heart, ≥0.8 units/μg protein, lyophilized powder,
cow

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PRKACA,
human
MISSION® esiRNA, targeting mouse Prkaca,
mouse