NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
동의어:
EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50
종:
Human NFKB1 (4790), Mouse Nfkb1 (18033), Rat Nfkb1 (81736), naked mole-rat Nfkb1 (101696485), sheep NFKB1 (101108228), cow NFKB1 (616115), dog NFKB1 (442859), domestic cat NFKB1 (100142683), Zebrafish nfkb1 (565756), chicken NFKB1 (396033)
UniProtKB ID:
Clone ID:
- Human(4790) Summary: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(18033) nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
- Rat(81736) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- naked mole-rat(101696485) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- sheep(101108228) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- cow(616115) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- dog(442859) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- domestic cat(100142683) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- Zebrafish(565756) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- chicken(396033) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- domestic guinea pig(100730075) nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
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Small Molecule - Antagonist
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-NFKB1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rat
응용분야
immunohistochemistry
western blot
western blot
Anti-NFKB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-NF-κB p105 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-NF-κB p105 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-NF-κB p105 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Small Molecule - Inhibitor
Proteins
제품 번호
설명
종