MAPK7
mitogen-activated protein kinase 7
BMK1, ERK4, ERK5, PRKM7
Human MAPK7 (5598), Mouse Mapk7 (23939), Rat Mapk7 (114509), Zebrafish mapk7 (541323), domestic cat MAPK7 (101097357), cow MAPK7 (537703), dog MAPK7 (489532), Domestic Rabbit MAPK7 (100338535), sheep MAPK7 (101110073), naked mole-rat Mapk7 (101726391)
- Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(23939) mitogen-activated protein kinase 7
- Rat(114509) mitogen-activated protein kinase 7
- Zebrafish(541323) mitogen-activated protein kinase 7
- domestic cat(101097357) mitogen-activated protein kinase 7
- cow(537703) mitogen-activated protein kinase 7
- dog(489532) mitogen-activated protein kinase 7
- Domestic Rabbit(100338535) mitogen-activated protein kinase 7
- sheep(101110073) mitogen-activated protein kinase 7
- naked mole-rat(101726391) mitogen-activated protein kinase 7
- domestic guinea pig(100728396) mitogen-activated protein kinase 7
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Antibodies
Anti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
human
Anti-ERK5 Antibody, clone 5C1P5, Rabbit Monoclonal, ,
human, rat
immunohistochemistry
western blot
western blot
Anti-MAPK7 antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence
Anti-MAPK7 (ab2) antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
human
western blot
Proteins
ERK5, active, GST tagged human, PRECISIOยฎ Kinase, recombinant, expressed in baculovirus infected Sf9 cells, โฅ70% (SDS-PAGE), buffered aqueous glycerol solution,
human