생물학적 소스
rabbit
Quality Level
material
colorless
클론
5C1P5, monoclonal
양식
liquid
분자량
115 kDa
종 반응성
human, rat, rat
농도
1
기술
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
색상
colorless
동형
IgG
면역원 서열
LSKSQVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MAPK7(5598)
일반 설명
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
면역원
A synthetic peptide corresponding to a sequence within amino acids 717-816 of human ERK5 (Q13164).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
애플리케이션
WB, IHC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
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