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Merck

KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1

동의어:
KIR1.1, ROMK, ROMK1
:
UniProtKB ID:
Clone ID:
  • Human(3758) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56379) potassium inwardly-rectifying channel, subfamily J, member 1
  • Rat(24521) potassium inwardly-rectifying channel, subfamily J, member 1
  • chicken(428236) potassium inwardly-rectifying channel, subfamily J, member 1
  • Horse(100072580) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic cat(101091140) potassium inwardly-rectifying channel, subfamily J, member 1
  • cow(539250) potassium inwardly-rectifying channel, subfamily J, member 1
  • dog(489285) potassium inwardly-rectifying channel, subfamily J, member 1
  • naked mole-rat(101720253) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic guinea pig(100722828) potassium inwardly-rectifying channel, subfamily J, member 1

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Small Molecule - Activator

제품 번호
설명
Diazoxide, ,
rat, mouse, human

Small Molecule - Antagonist

제품 번호
설명
Glyburide, meets USP testing specifications,
rat, human
Cromakalim, ,
rat
Glybenclamide, ≥99% (HPLC),
rat, human
Chlorpropamide, analytical standard, ≥97%,
human, mouse
Tolbutamide, analytical standard,
human, mouse

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-KCNJ1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, guinea pig, horse, human, rabbit, rat
응용분야
western blot
Anti-ROMK antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence
Anti-KCNJ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-KCNJ1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Blocker

제품 번호
설명
Glipizide, solid,
human
Repaglinide, ≥98% (HPLC), solid,
human
Glimepiride, ≥98% (HPLC), solid,
human
Glyburide, meets USP testing specifications,
rat, human
Glybenclamide, ≥99% (HPLC),
rat, human

Small Molecule - Inhibitor

제품 번호
설명
Linopirdine, ≥98% (HPLC),
rat
VU591, ≥98% (HPLC),
human
Tertiapin-Q trifluoroacetate salt, ≥97% (HPLC),
rat, human, mouse
Chlorpropamide, analytical standard, ≥97%,
human, mouse
Tolbutamide, analytical standard,
human, mouse

Small Molecule - Ligand

제품 번호
설명
Glipizide, solid,
human
Glimepiride, ≥98% (HPLC), solid,
human
Glybenclamide, ≥99% (HPLC),
rat, human
Chlorpropamide, analytical standard, ≥97%,
human, mouse

Small Molecule - Opener

제품 번호
설명
Minoxidil, ≥99% (TLC),
human
Diazoxide, ,
rat, mouse, human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human KCNJ1,
human