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Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

동의어:
LNCR2, NACHRA3, PAOD2
:
UniProtKB ID:
Clone ID:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3

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Small Molecule - Agonist

제품 번호
설명
(±)-Nicotine, ≥99% (TLC), liquid,
human, rat
Carbamoylcholine chloride, ≥98% (titration), crystalline,
human, mouse, rat
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
rat, human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
human, mouse, rat

Small Molecule - Antagonist

제품 번호
설명
Cytisine, ≥99%, powder,
rat
(±)-Nicotine, ≥99% (TLC), liquid,
human, rat
Carbamoylcholine chloride, ≥98% (titration), crystalline,
human, mouse, rat
Mecamylamine hydrochloride, ,
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, human, rabbit
응용분야
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
종별 반응성
chicken, eel, human
응용분야
immunohistochemistry

Small Molecule - Blocker

제품 번호
설명
Hexamethonium chloride, solid (hygroscopic),
human
Tetraethylammonium chloride, ≥98% (titration),
human
Hexamethonium bromide, ,
human
Kynurenic acid, ≥98%,
rat, human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CHRNA3,
human
MISSION® esiRNA, targeting mouse Chrna3,
mouse