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Merck

AGTR1

angiotensin II receptor, type 1

동의어:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
:
UniProtKB ID:
Clone ID:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Agonist

제품 번호
설명
ProteoMass Angiotensin II MALDI-MS Standard, vial of 10 nmol,
human
[Val5]-Angiotensin II acetate salt hydrate, ≥95% (HPLC), powder,
mouse, human, rat
[Asn1, Val5]-Angiotensin II, ≥97% (HPLC),
mouse, human, rat

Small Molecule - Antagonist

제품 번호
설명
Valsartan, ≥98% (HPLC),
human
Candesartan cilexetil, ≥98% (HPLC),
human
Eprosartan mesylate, ≥98% (HPLC),
human
Losartan potassium, European Pharmacopoeia (EP) Reference Standard,
human
Losartan potassium, ,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
응용분야
western blot
Anti-AGTR1/AT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
ELISA
western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
종별 반응성
human, mouse, rat
응용분야
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
bovine, canine, human, mouse, rat
응용분야
affinity binding assay
immunocytochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Captopril, ≥98% (HPLC), powder,
human, rat
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
human, rat, mouse

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human AGTR1,
human