SBNMQ
NMQ/N-methyl-quinidine - MDR1/P-gp Substrate
Synonym(s):
SB-NMQ, N-methyl-quinidine (NMQ), NMQ
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C21H27IN2O2
CAS Number:
Molecular Weight:
466.36
UNSPSC Code:
12352200
NACRES:
NA.84
Recommended Products
form
powder
color
white
storage temp.
room temp
InChI
1S/C21H27N2O2.HI/c1-4-14-13-23(2)10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-3)12-18(17)19;/h4-7,9,12,14-15,20-21,24H,1,8,10-11,13H2,2-3H3;1H/q+1;/p-1/t14-,15?,20+,21-,23?;/m0./s1
InChI key
AJQSDVGBERUTGX-QVEQJUGRSA-M
Application
NMQ/N-methyl-quinidine - MDR1/P-gp substrate has been used as a probe substrate for multidrug resistance protein 1 (MDR1) in vesicles assay.
Biochem/physiol Actions
SOLVO Biotechnology offers NMQ as a selective substrate for the MDR1 membrane transporter.
NMQ was shown to be actively transported by human MDR1/P-gp and rat Mdr1b efflux transporters.
NMQ was shown to be actively transported by human MDR1/P-gp and rat Mdr1b efflux transporters.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Potential herb-drug interaction of shexiang baoxin pill in vitro based on drug metabolism/transporter.
Shen Z, et al.
American Journal of Translational Research, 8(12), 5545-5545 (2016)
Zhijie Shen et al.
American journal of translational research, 8(12), 5545-5556 (2017-01-13)
Many researches have proved functions of anti-oxidation, endothelial protection and pro-angiogenesis efficiency of Shexiang Baoxin Pill (SBP). This study aims to investigate potential for metabolism-based interaction on CYP450s and transporter based interaction on OATP1B1, BRCP and MDR1. Human primary hepatocytes
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service