SAB5700424

Anti-Phospho-VEGF Receptor 2-Y996 antibody produced in rabbit

• Synonym(s): CD309, FLK1, KDR, VEGF Receptor 2, VEGFR, VEGFR2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 151; 75; 79
• species reactivity: human
• concentration: 1.13 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P35968
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr996)
• Gene Information: human ... KDR(3791)

Description

General description

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Immunogen

A synthetic phosphorylated peptide around Y996 of human VEGF Receptor 2 (NP_002244.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable