Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
Immunogen
APOC3 (NP_000031, 68-102) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human APOC3.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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