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Key Documents

PZ0359

Sigma-Aldrich

PF-06827443

≥98% (HPLC)

Synonym(s):

2-((3R,4S)-3-Hydroxytetrahydro-pyran-4-yl)-5-methyl-6-(4-oxazol-4-yl-benzyl)-2,3-dihydro-isoindol-1-one

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5 MG
₩103,936
25 MG
₩421,530

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Estimated to ship onMay 07, 2025Details

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5 MG
₩103,936
25 MG
₩421,530

About This Item

Empirical Formula (Hill Notation):
C24H24N2O4
CAS Number:
Molecular Weight:
404.46
UNSPSC Code:
51111800
NACRES:
NA.77

₩103,936


Estimated to ship onMay 07, 2025Details

New, lower price on this item!

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Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

room temp

SMILES string

CC1=CC(CN([C@@H]2[C@@H](O)COCC2)C3=O)=C3C=C1CC4=CC=C(C5=COC=N5)C=C4

InChI

1S/C24H24N2O4/c1-15-8-19-11-26(22-6-7-29-13-23(22)27)24(28)20(19)10-18(15)9-16-2-4-17(5-3-16)21-12-30-14-25-21/h2-5,8,10,12,14,22-23,27H,6-7,9,11,13H2,1H3/t22-,23-/m0/s1

InChI key

RBMHKFVYRIRMOG-GOTSBHOMSA-N

Biochem/physiol Actions

PF-06827443 is a otent, low clearance, orally bioavailable, and CNS penetrant muscarinic M1-selectivepositive allosteric modulator (PAM) with minimal agonist activity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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