E-Toxate™ Kit prepared from Limulus polyphemus amebocyte lysate (LAL) is suitable for the detection and quantification of endotoxins for research purposes.
Application
E-Toxate™ Kit has been used to determine the endotoxins:
from Tabebuia chrysantha and Tabebuia rosea plant methanolic extracts
from human pentameric C-reactive protein (pCRP)
in the Diptheria toxin preparations
The E-TOXATE Kit was used to determine the number of bacteria in suspensions of group B streptococci used to infect rats for models of sepsis. [1]
Features and Benefits
Highly sensitive to endotoxins
Simple and rapid detection
Cost-effective
Legal Information
E-Toxate is a trademark of Sigma-Aldrich Co. LLC
Kit Components Also Available Separately
Product No.
Description
SDS
E8029E-Toxate™ Endotoxin standard, for endotoxin quantitation 1 mL/vialSDS
E8779E-Toxate™ reagent from Limulus polyphemus, sufficient for 20 tests 1 mL/vialSDS
Memorias do Instituto Oswaldo Cruz, 103(3), 244-250 (2008-06-12)
A polysaccharide-rich fraction (ATF) of medicinal mushroom Agaricus brasiliensis was evaluated on the candidacidal activity, H2O2 and nitric oxide (NO) production, and expression of mannose receptors by murine peritoneal macrophages. Mice received three intraperitoneal (i.p.) injections of ATF and after
The Journal of biological chemistry, 280(30), 27935-27948 (2005-06-01)
Excessive angiogenesis is involved in many human diseases, and inhibiting angiogenesis is an important area of drug development. There have been conflicting reports as to whether decorin could function as an angiogenic inhibitor when used as an extracellular soluble factor.
Priscila Raquel Martins et al.
The journal of venomous animals and toxins including tropical diseases, 23, 17-17 (2017-03-28)
Agaricus brasiliensis is a medicinal mushroom with immunomodulatory and antitumor activities attributed to the β-glucans presented in the polysaccharide fraction of its fruiting body. Since β-glucans enhance cellular immunoresponsiveness, in this study we aimed to evaluate the effect of an
The American journal of pathology, 176(1), 218-226 (2009-12-02)
To investigate the role of CD11c(+) cells in endotoxin-induced acute lung injury, wild-type or CD11c-diphtheria toxin receptor transgenic mice were treated with intraperitoneal diphtheria toxin (5 ng/g b.wt.) in the presence or absence of intratracheal lipopolysaccharide (51 microg). Lipopolysaccharide treatment
Molecular therapy : the journal of the American Society of Gene Therapy, 14(4), 588-598 (2006-05-31)
Excessive complement activation can result in extreme tissue damage and systemic inflammatory responses, similar to innate immune responses rapidly elicited after systemic adenovirus (Ad) injections. To determine if Ad interactions with the complement system impact upon Ad-induced innate immune responses
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