B7216
Bleomycin
liquid, non-animal origin, suitable for cell culture, BioReagent
Synonym(s):
BLM, BLM A2, Blenoxane, Bleo, Bleomycin, Bleomycin A2, Blexane
About This Item
Recommended Products
product name
Bleomycin ready made solution, Cell culture tested, 10 mg/mL in H2O, 0.2 μm filtered
Quality Level
sterility
0.2 μm filtered
form
liquid
storage condition
protect from light
concentration
10 mg/mL in H2O
storage temp.
−20°C
Related Categories
General description
Bleomycin has several important applications:
- Bleomycin has been used to induce chronic lung disease in animal models as part of a research to find antifibrotic therapy for COVID-19 (SARS-CoV-2).
- Bleomycin - induced pulmonary fibrosis in-vivo experiments performed in mice by dose administration of 0.25-2mg/Kg.
- Bleomycin serves as a selective agent for gram-negative and gram-positive bacteria. Bleomycin cause DNA cleavage through formation of 1:1 complex with BLE protein. The resistance is obtained by encoding the ble gene of BLE protein from Streptoalloteichus hindustanus which prevents DNA cleavage.
- Bleomycin can be used for selection in different types of cell lines.
Bleomycin suggested concentration range for cell selection is 10-100μg/mL. Hence, it is recommended to dilute the ready made solution 1:100-1,000 in media of choice.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Muta. 1B
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 2
Certificates of Analysis (COA)
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