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05-0015

Sigma-Aldrich

Cacodylic acid

SAJ first grade

Synonym(s):

Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide

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About This Item

Linear Formula:
(CH3)2As(O)OH
CAS Number:
75-60-5
Molecular Weight:
138.00
Beilstein:
1736965
EC Number:
200-883-4
MDL number:
MFCD00002095
UNSPSC Code:
12352106
PubChem Substance ID:
329748000
Pricing and availability is not currently available.

grade

SAJ first grade

form

solid

reaction suitability

reagent type: catalyst
core: arsenic

availability

available only in Japan

SMILES string

C[As](C)(O)=O

InChI

1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)

InChI key

OGGXGZAMXPVRFZ-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

H301 + H331,H350,H410

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
A1379

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Hua Naranmandura et al.
Toxicological sciences : an official journal of the Society of Toxicology, 128(1), 137-146 (2012-04-28)
Arsenic is known to be a human carcinogen as well as one of the most effective drugs for treatment of patients with acute promyelocytic leukemia. The intermediate metabolites of arsenic, monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)), are formed by
S Yamamoto et al.
Mutation research, 386(3), 353-361 (1997-06-01)
The modifying effects of dimethylarsinic acid (DMA), the major metabolite of ingested arsenicals in most mammals, on chemical carcinogenesis were investigated using rat in vivo models and reviewed here. In a multi-organ bioassay, rats pretreated with 5 carcinogens were administered
Erik J Tokar et al.
Toxicology letters, 209(2), 179-185 (2012-01-11)
Inorganic arsenic, an early life carcinogen in humans and mice, can initiate lesions promotable by other agents in later life. The biomethylation product of arsenic, dimethylarsinic acid (DMA), is a multi-site tumor promoter. Thus, pregnant CD1 mice were given drinking
Larissa Leffers et al.
Toxicology, 305, 109-119 (2013-01-29)
Inorganic arsenic is a well-documented, exposure relevant human carcinogen. A promising starting point to further understand the mechanisms behind inorganic arsenic carcinogenicity might be a formation of reactive, highly toxic metabolites during human arsenic metabolism. This study characterises the toxicity
Hua Naranmandura et al.
Analytical and bioanalytical chemistry, 405(6), 1885-1891 (2012-06-27)
Arsenic (+3 oxidation state) methyltransferase (As3mt) plays a central role in the enzymatically catalyzed conversion of inorganic arsenic into methylated metabolites. Most studies of the metabolism and disposition of arsenicals following exposure to inorganic arsenic focus on the formation and
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