MABT1528

Anti-Claudin 5 Antibody, clone 2B12

• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• antibody form: purified antibody
• clone: 2B12; monoclonal
• purified by: using protein G
• species reactivity: human, human, mouse
• concentration: (Please refer to lot specific datasheet.)
• technique(s): ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG2aκ
• UniProt accession no.: O00501
• Mode of action: | inhibits

Description

General description

An artificial membrane protein consisting of the extracellular region of human Claudin 5.

Specificity

Clone 2B12 is a mouse monoclonal antibody that detects human Claudin 5. It targets an epitope within nine amino acids in the second extracellular domain.

Application

Epitope: extracellular domain

Quality

Evaluated by Flow Cytometry in human umbilical vein endothelial cells (HUVEC).

Flow Cytometry Analysis: 1 µg of this antibody detected Claudin 5 one million human umbilical vein endothelial cells (HUVEC).

Physical properties

23.15 kDa calculated.

Physical form

Purified mouse monoclonal antibody IgG2a in PBS without azide.

Storage and Stability

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.