Detect Presenilin 1 using this Anti-Presenilin 1 Antibody validated for use in ELISA & WB.
Immunoblotting: 1:1,000-1:4,000. To minimize background staining it is suggested that you include a higher content of detergent (Tween-20) in your dilution and washing solutions.
Immunohistochemistry: not tested. It is recommended that you try the antibody at 1:50-1:500.
ELISA: 1:1,000-1:4,000
Optimal working dilutions must be determined by the end user.
Research Category Neuroscience
Research Sub Category Neurodegenerative Diseases
Physical form
Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
The Journal of biological chemistry, 291(42), 22276-22287 (2016-09-01)
Accumulation of amyloid-β peptide (Aβ) in the brain is regarded as central to Alzheimer's disease (AD) pathogenesis. Aβ is generated by a sequential cleavage of amyloid precursor protein (APP) by β-secretase 1 (BACE-1) followed by γ-secretase. BACE-1 cleavage of APP
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
