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8.55056

Sigma-Aldrich

Hydroxylamine NovaTag® resin

Novabiochem®

Synonym(s):

N-Boc 2Aoa-NÆ-Fmoc-ethylenediamine MPB-AM resin

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About This Item

UNSPSC Code:
12352116

Quality Level

product line

NovaSyn® TG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

15-25°C

General description

Hydroxylamine NovaTag resin is an ideal tool for the synthesis of peptides labeled at the C-terminus with an hydroxylamine group. Such peptides readily undergo oxime formation in aqueous media with aldehyde-modified proteins or peptides, MAP core peptides, or surfaces. For the synthesis of MAPs, this approach avoids many of the problems associated with their purification and analysis, since the linear peptide antigen can be fully characterized prior to conjugation with the pre-formed lysine tree.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Linkage

Replaces: 04-12-3909

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.20 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene-1 % DVB), 100 -200 mesh

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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