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07-280

Sigma-Aldrich

Anti-PEDF Antibody

Upstate®, from rabbit

Synonym(s):

Anti-EPC-1, Anti-OI6, Anti-PEDF, Anti-PIG35

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SERPINF1(5176)

Specificity

PEDF

Immunogen

His tagged fusion protein corresponding to full length human PEDF (Pigment Epitheliuml Derived Factor) expressed in baby hamster kidney cells

Application

Anti-PEDF Antibody is an antibody against PEDF for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Quality

routinely evaluated by immunoblot on RIPA lysates from Y79 cells

Target description

50kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Huixia Lu et al.
Frontiers in pharmacology, 8, 783-783 (2017-11-29)
Angiogenesis is the formation of new blood vessels from the existing vasculature, which is involved in multiple biological processes, including atherosclerosis, ischemic heart disease, and cancer. Ginsenoside-Rb1 (Rb1), the most abundant ginsenoside isolated form Panax ginseng, has been identified as
Fei Zhang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(9), 3730-3740 (2013-06-05)
Tissue perivascular resident macrophages (PVM/Ms), a hybrid cell type with characteristics of both macrophages and melanocytes, are critical for establishing and maintaining the endocochlear potential (EP) required for hearing. The PVM/Ms modulate expression of tight- and adherens-junction proteins in the
P C Karakousis et al.
Molecular vision, 7, 154-163 (2001-07-05)
To localize pigment epithelium-derived factor (PEDF) in developing and adult human ocular tissues. PEDF was localized in fetal and adult eyes by immunofluorescence with a polyclonal antibody (pAb) against amino acids 327-343 of PEDF, or a monoclonal antibody (mAb) against
Sofia M Calado et al.
Molecular vision, 22, 761-770 (2016-07-22)
In this study, we aimed to understand whether glucose transporter 1 (GLUT1) activity affects the secretion capacity of antiangiogenic factor pigment epithelium-derived factor (PEDF) by the RPE cells, thus explaining the reduction in PEDF levels observed in patients with diabetic
Pu Zhang et al.
International journal of ophthalmology, 14(5), 656-665 (2021-05-21)
To evaluate the protective mechanisms of piperine in the retina of mice with streptozotocin-induced diabetes. In experiments in vitro, stimulation by chemical hypoxia was established in ARPE-19 cells. Then, the expression of hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor A

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