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P-021

Supelco

Phenylbutazone solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C19H20N2O2
CAS Number:
50-33-9
Molecular Weight:
308.37
EC Number:
200-835-2
UNSPSC Code:
41116107

grade

certified reference material

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

concentration

1.0 mg/mL in acetonitrile

format

single component solution

storage temp.

−20°C

SMILES string

CCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3

General description

Phenylbutazone is a non steroidal anti-inflammatory drug (NSAID) used for pain and fever relief. This Certified Spiking Solution® is applicable for use in LC/MS or GC/MS applications for clinical toxicology or forensic analysis. No longer approved for human use in the USA or UK, phenylbutazone continues to be used in horses and dogs.

Legal Information

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

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Chang Yi Kong et al.
Journal of chromatography. A, 1279, 92-97 (2013-02-02)
The diffusion coefficients D(12) of phenylbutazone at infinite dilution in supercritical CO(2) were measured by the chromatographic impulse response (CIR) method. The measurements were carried out over the temperature range from 308.2 to 343.2 K at pressures up to 40.0
Ali Asghar Mozaffari et al.
Tropical animal health and production, 43(7), 1389-1393 (2011-04-20)
The purpose of this study was to evaluate the brain, renal, and hepatic effects of three NSAIDs (flunixin meglumine, ketoprofen, and phenylbutazone) when administered IV to clinically normal Iranian fat-tailed sheep. The experiments were conducted on twenty clinically normal adult
J H Foreman et al.
Equine veterinary journal. Supplement, (38)(38), 601-605 (2011-05-27)
Objective blinded efficacy data during exercise are lacking on the use of single-dose i.v. nonsteroidal anti-inflammatory drugs (NSAIDs) before, during and after exercise. Single i.v. doses of either phenylbutazone (PBZ) or flunixin meglumine (FM) would prove more efficacious than negative
Véronique Gayrard et al.
General and comparative endocrinology, 174(2), 225-231 (2011-09-22)
A model of thyroidectomized sheep intravenously supplemented with thyroid hormone (TH) was developed to mimic endogenous TH exposure and to analyze the impact on plasma TH homeostasis of xenobiotic interference with TH binding to plasma proteins. TH was displaced from
Bute residues of low concern for consumers, say EFSA and EMA.
The Veterinary record, 172(16), 407-407 (2013-04-23)
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