Skip to Content
Merck
All Photos(1)

Documents

900150O

Avanti

CoQ6

Avanti Research™ - A Croda Brand 900150O

Synonym(s):

Coenzyme Q6 (S. cerevisiae)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C39H58O4
CAS Number:
1065-31-2
Molecular Weight:
590.88
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mg (900150O-1mg)
pkg of 1 × 5 mg (900150O-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 900150O

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(C(OC)=C1OC)C(C)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)C1=O

InChI

1S/C39H58O4/c1-28(2)16-11-17-29(3)18-12-19-30(4)20-13-21-31(5)22-14-23-32(6)24-15-25-33(7)26-27-35-34(8)36(40)38(42-9)39(43-10)37(35)41/h16,18,20,22,24,26H,11-15,17,19,21,23,25,27H2,1-10H3/b29-18+,30-20+,31-22+,32-24+,33-26+

InChI key

GXNFPEOUKFOTKY-LPHQIWJTSA-N

General description

Coenzyme Q6 (CoQ6) is also known as ubiquinone-30 in Saccharomyces cerevisiae. It is a flavoprotein that utilizes flavin adenine dinucleotide (FAD) as a co-factor for the synthesis of coenzyme Q. It is composed of three conserved regions- a FAD/ nicotinamide adenine dinucleotide (NAD) + hydrogen (H) (NADH) binding motif, an adenine di phosphate (ADP) binding motif and a consensus sequence, that binds to the ribityl moiety of FAD.

Application

CoQ6 has been used:
  • as an internal standard for the liquid-chromatography mass-spectrometry for the quantification of CoQ6
  • to determine its effect on peroxisome proliferator-activated receptor (PPAR)
  • in reversed-phase high pressure liquid chromatography to quantify yeast quinones

Biochem/physiol Actions

Coenzyme Q6 (CoQ6) in the plasma membrane of Saccharomyces cerevisiae is involved in the ascorbate stabilization at the plasma membrane.

Packaging

2 mL Amber Glass Sealed Ampule (900150O-1mg)
2 mL Amber Glass Sealed Ampule (900150O-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Coenzyme Q biosynthesis: evidence for a substrate access channel in the FAD-dependent monooxygenase Coq6
Ismail A, et al.
PLoS Computational Biology, 12(1) (2016)
Biosynthesis of coenzyme Q in eukaryotes
Kawamukai M
Bioscience, Biotechnology, and Biochemistry, 80(1), 23-33 (2016)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
Testing, 7(6) (2012)
Idebenone and coenzyme Q10 are novel PPAR alpha gamma ligands, with potential for treatment of fatty liver diseases
Tiefenbach J, et al.
Disease models & mechanisms, 11(9) (2018)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
PLoS ONE, 7(6) (2012)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service