QBD10262

m-dPEG^®₁₂-NHS ester

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₃₀H₅₅NO₁₆
• Molecular Weight: 685.75
• MDL number: MFCD13184970
• UNSPSC Code: 12352108
• PubChem Substance ID: 329823902
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
• InChI: 1S/C30H55NO16/c1-35-6-7-37-10-11-39-14-15-41-18-19-43-22-23-45-26-27-46-25-24-44-21-20-42-17-16-40-13-12-38-9-8-36-5-4-30(34)47-31-28(32)2-3-29(31)33/h2-27H2,1H3
• InChI key: ZMXRHHJWXLKMTL-UHFFFAOYSA-N

Description

Features and Benefits

The m-dPEG^®₁₂-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₁₂-NHS (N-hydroxysuccinimide) ester reacts with amines.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable