P63204
2,3-Pyridinedicarboxylic acid
99%
Synonym(s):
Quinolinic acid
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₩69,325
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25 G
₩69,325
100 G
₩123,120
About This Item
Empirical Formula (Hill Notation):
C7H5NO4
CAS Number:
Molecular Weight:
167.12
Beilstein:
137110
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form:
powder
Assay:
99%
Recommended Products
Quality Level
Assay
99%
form
powder
mp
188-190 °C (dec.) (lit.)
SMILES string
OC(=O)c1cccnc1C(O)=O
InChI
1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)
InChI key
GJAWHXHKYYXBSV-UHFFFAOYSA-N
Gene Information
rat ... Gria1(50592) , Grin2a(24409)
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Related Categories
Application
Inhibits glucose synthesis.[1]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Dorit Cohen-Carmon et al.
Molecular neurobiology, 57(3), 1768-1777 (2019-12-14)
Huntington's disease (HD) is a neurodegenerative late-onset genetic disorder caused by CAG expansions in the coding region of the Huntingtin (HTT) gene, resulting in a poly-glutamine (polyQ) expanded HTT protein. Considerable efforts have been devoted for studying HD and other
L Garcia-Salguero et al.
Archives internationales de physiologie, de biochimie et de biophysique, 99(3), 237-242 (1991-06-01)
The in vitro and in vivo effects of several different inhibitors of carbohydrate metabolism have been studied. The in vitro addition of 5-methoxyindole-2-carboxylic acid (MICA), pent-4-enoic acid, and quinolinic acid to the perfusion medium significantly inhibited liver gluconeogenesis in 48-hour-starved
F Moroni et al.
Journal of neurochemistry, 47(6), 1667-1671 (1986-12-01)
Quinolinic acid (QUIN), an excitotoxic tryptophan metabolite, has been identified and measured in human cerebrospinal fluid (CSF) using a mass-fragmentographic method. Furthermore, its content has been evaluated in frontal cortex obtained at autopsy from the cadavers of patients who died
Valéry Combes et al.
Trends in parasitology, 28(8), 311-319 (2012-06-26)
Homeostasis implies constant operational defence mechanisms, against both external and internal threats. Infectious agents are prominent among such threats. During infection, the host elicits the release of a vast array of molecules and numerous cell-cell interactions are triggered. These pleiomorphic
Gilles J Guillemin et al.
Neuro-degenerative diseases, 2(3-4), 166-176 (2006-08-16)
The kynurenine pathway (KP) is a major route of L-tryptophan catabolism leading to production of several neurobiologically active molecules. Among them is the excitotoxin quinolinic acid (QUIN) that is known to be involved in the pathogenesis of several major inflammatory
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