763896
DL-α-Tocopherol methoxypolyethylene glycol succinate
Synonym(s):
Polyethylene glycol, TPGS-750-M
About This Item
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form
powder
Quality Level
reaction suitability
reagent type: catalyst
reaction type: C-H Activation
reagent type: surfactant
greener alternative product characteristics
Catalysis
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
transition temp
Tm 29-34
greener alternative category
, Aligned
General description
Application
TPGS-750-M can also be employed in:
- The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions.
- The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp2)-H hydroxylation reaction.
- The intramolecular N-arylation of amines using a copper catalyst.
Other Notes
From milligrams to kilograms: synthetic chemistry following nature′s lead
related product
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Articles
Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.
Micellular catalysis has provided the ability to carry out several commonly used transformations used in the synthetic community to be carried out in water.
Surfactants for efficient reactions in water as a green chemistry alternative.
A variety of palladium-catalyzed cross-coupling reactions can be run under room temperature conditions in water with TPGS- 750-M, using a variety of commercially available palladium complexes and ligands.
Protocols
TPGS-750-M surfactant enables various reactions in water at room temperature, enhancing efficiency and versatility in synthesis.
Related Content
Prof. Bruce Lipshutz and co-workers have developed designer surfactants to allow several classes of transformations (e.g. Suzuki-Miyaura, Olefin Metathesis, 1,4-Addition to Enones, etc.) to be performed in water.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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