532592

4-Methyl-3-nitropyridine

97%

• Empirical Formula (Hill Notation): C₆H₆N₂O₂
• CAS Number: 5832-44-0
• Molecular Weight: 138.12
• MDL number: MFCD00051829
• UNSPSC Code: 12352100
• PubChem Substance ID: 24877898
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• refractive index: n20/D 1.549
• bp: 238 °C
• mp: 24-28 °C
• density: 1.228 g/mL at 25 °C
• SMILES string: Cc1ccncc1[N+]([O-])=O
• InChI: 1S/C6H6N2O2/c1-5-2-3-7-4-6(5)8(9)10/h2-4H,1H3
• InChI key: JLNRJMGYBKMDGI-UHFFFAOYSA-N

Description

General description

4-Methyl-3-nitropyridine, a substituted nitropyridine, can be prepared by the malonation of 4-methoxy-3-nitropyridine with sodium diethyl malonate.

Application

4-Methyl-3-nitropyridine may be used as a starting material in the synthesis of ethyl 6-azaindole-2-carboxylate and also 3-substituted azaindoles.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H315,H318,H335
• Precautionary Statements: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 226.9 °F - closed cup
• Flash Point(C): 108.3 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves