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438227

Sigma-Aldrich

Hydroxylamine solution

50 wt. % in H2O

Synonym(s):

HDA

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About This Item

Linear Formula:
NH2OH
CAS Number:
7803-49-8
Molecular Weight:
33.03
EC Number:
232-259-2
MDL number:
MFCD00044522
UNSPSC Code:
12352116
PubChem Substance ID:
24867438
NACRES:
NA.22

vapor pressure

9 mmHg ( 40 °C)

Quality Level

200

form

liquid

concentration

50 wt. % in H2O

bp

>100 °C

density

1.078 g/mL at 25 °C

SMILES string

NO

InChI

1S/H3NO/c1-2/h2H,1H2

InChI key

AVXURJPOCDRRFD-UHFFFAOYSA-N

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General description

Hydroxylamine is a weak base that is mainly used as a reducing agent in organic reactions.

Application

Reactant for preparation of:
  • Prodrug for cardiovascular agent Nω-hydroxy-L-arginine (NOHA, nitric oxide precursor)
  • Hydroxyaminoguanidines as anti-cancer agents
  • Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced phosphoenolpyruvate caboxykinase (PEPCK) transactivation
  • Carboxamide derivatives of ofloxacin with improved antimicrobial properties
  • Analogues of coumarin based TNF-α converting enzyme (TACE) inhibitors
  • HIV integrase inhibitors

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Target Organs

Blood, Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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