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408700

Sigma-Aldrich

Poly(ethyleneimine) solution

average Mw 1800, 50 wt. % in H2O

Synonym(s):

Ethyleneimine polymer solution, PEI

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5 ML
₩98,455
250 ML
₩203,711
1 L
₩553,987

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5 ML
₩98,455
250 ML
₩203,711
1 L
₩553,987

About This Item

CAS Number:
9002-98-6
MDL number:
MFCD00084427
UNSPSC Code:
12162002
PubChem Substance ID:
24865590
NACRES:
NA.23

₩98,455

In StockDetails

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form

liquid

Quality Level

200

mol wt

average Mw 1800

concentration

50 wt. % in H2O

refractive index

n20/D 1.453

density

1.08 g/mL at 25 °C

SMILES string

N1CC1.NCCN

InChI

1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2

InChI key

SFLOAOINZSFFAE-UHFFFAOYSA-N

General description

Poly(ethyleneimine) (PEI) is a positivelycharged polymeric amine with a linear or branched structure. It has chelating properties with a variety of metal ions. It is highlysoluble in water and behaves as an effective base in aqueous solutions. Due toits superior physicochemical properties, it is widely used in the field ofbiomedicine, water purification, bioimaging, gene delivery, and self-healingmaterials.

Application

Poly(ethyleneimine) solution can be used for surface modification of cation exchange resins. The modified resins exhibited improved selectivity towards transition elements. Due to repulsion effects within the cationic layer, the selectivity for alkaline ions decreases. As a result, this resin can be applied to purify industrial waste by column sorption.

It can be used as a precursor to prepare polyelectrolyte multilayers for the promotion of cell adhesion and growth on implant surfaces.

PEI can act as a reactive template and stabilizing agent in the preparation of metal nanoparticles in aqueous media. The amino groups in the PEI can coordinate with metal ions dissolved in water and reduce their aggregation capability. This results in the formation of smaller nanoparticles.

Features and Benefits

  • It has repetitive structural units and aflexible polymer chain.
  • Due to the accessibility of a huge number ofamino groups on PEI, it can be modified or functionalized for specific featuressuch as sensitivity, specificity, and biocompatibility.
  • Highwater solubility.

Physical form

Branched polymer

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF2562V
MKCV8284
MKCW0769
WXBF4554V
MKCV0916

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Laura R H Ip et al.
Oncotarget, 6(12), 10548-10562 (2015-04-15)
Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI3K/Akt pathway with
Jonathon M Muncie et al.
Developmental cell, 55(6), 679-694 (2020-11-19)
Embryogenesis is directed by morphogens that induce differentiation within a defined tissue geometry. Tissue organization is mediated by cell-cell and cell-extracellular matrix (ECM) adhesions and is modulated by cell tension and tissue-level forces. Whether cell tension regulates development by modifying
Diana F Silva et al.
Journal of neuroinflammation, 17(1), 332-332 (2020-11-07)
After decades of research recognizing it as a complex multifactorial disorder, sporadic Alzheimer's disease (sAD) still has no known etiology. Adding to the myriad of different pathways involved, bacterial neurotoxins are assuming greater importance in the etiology and/or progression of

Articles

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

Microfluidics for Nanoencapsulation of Nucleic Acids

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the molar ratio of the amino groups (primary, secondary, tertiary) present in polyethyleneimine 408700?

    1 answer

    1. This molar ratio of amino groups is not determined for this product, however, this compound is essentially identical to Lupasol G35. BASF reports that Lupasol G35 has a ratio of primary:secondary:tertiary amine groups of about 1.5:1.4:1.

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