364401

Dimethylzinc solution

2.0 M in toluene

• Synonym(s): Dimethylzinc
• Linear Formula: (CH₃)₂Zn
• CAS Number: 544-97-8
• Molecular Weight: 95.46
• Beilstein: 3587195
• MDL number: MFCD00014854
• UNSPSC Code: 12352103
• PubChem Substance ID: 24862428
• NACRES: NA.22

Properties

• Quality Level: 100
• concentration: 2.0 M in toluene
• density: 0.931 g/mL at 25 °C
• SMILES string: C[Zn]C
• InChI: 1S/2CH3.Zn/h2*1H3;
• InChI key: AXAZMDOAUQTMOW-UHFFFAOYSA-N

Description

Application

Dimethylzinc can be used as:

• A catalyst with nickel for the stereoselective C−2 alkenylation and dialkenylation of pyridine derivatives by alkynes to give monoalkenylation products.
• A reagent with aldehydes and 2-methoxyaniline for the enantioselective synthesis of alkyl and aralkyl secondary amines via one-pot three-component coupling reaction in the presence of zirconium tetraisopropoxide.
• A methylating reagent for the methylation of fluoroalkylated pyruvates in the presence of a copper/chiral diphosphine catalyst.
• An activator for radical trifluoromethylation of silyl enol ethers leading to α-trifluoromethyl ketones.

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H225,H250,H260,H304,H314,H336,H361d,H373,H410
• Precautionary Statements: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 - STOT SE 3 - Water-react 1
• Target Organs: Central nervous system
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 3
• Flash Point(F): 1.4 °F - closed cup
• Flash Point(C): -17 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves