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32008

Sigma-Aldrich

1,2-Diethylbenzene

≥99.0% (GC)

Synonym(s):

o-Diethylbenzene

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₩144,942
5 ML
₩496,335

₩144,942


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1 ML
₩144,942
5 ML
₩496,335

About This Item

Linear Formula:
C6H4(C2H5)2
CAS Number:
Molecular Weight:
134.22
Beilstein:
1904392
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

₩144,942


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Quality Level

Assay

≥99.0% (GC)

autoignition temp.

743 °F

refractive index

n20/D 1.502 (lit.)
n20/D 1.503

bp

183 °C (lit.)

mp

−31 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

SMILES string

CCc1ccccc1CC

InChI

1S/C10H14/c1-3-9-7-5-6-8-10(9)4-2/h5-8H,3-4H2,1-2H3

InChI key

KVNYFPKFSJIPBJ-UHFFFAOYSA-N

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General description

1,2-Diethylbenzene can be used as a reactant in the preparation of pseudocyclic diaryliodonium triflates, 5,6-disubstituted indanone intermediates via intramolecular Friedel-Crafts alkylation, dibromide intermediates via radical bromination, and in the dehydrogenative C-H/C-H arylation of indolines[1][2][3][4].

Application

  • Attraction of adult Harmonia axyridis to volatiles of the insectary plant Cnidium monnieri: This study investigates the attraction of the beetle Harmonia axyridis to 1,2-diethylbenzene, indicating potential uses in biological control strategies (Zhiping et al., 2020).

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

131.0 °F - closed cup

Flash Point(C)

55 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of arylbenziodoxoles using pseudocyclic benziodoxole triflate and arenes
Yoshimura A, et al.
ARKIVOC (Gainesville, FL, United States), 2020 (2021)
Formation of 4, 5, 6, 7-tetrahydroisoindoles by palladium-catalyzed hydride reduction
Hou D, et al.
The Journal of Organic Chemistry, 72 (2007)
Exceptionally Mild Palladium (II)-Catalyzed Dehydrogenative C--H/C--H Arylation of Indolines at the C-7 Position under Air
Jiao L, et al.
Organic Letters, 16 (2014)
J P Payan et al.
Drug metabolism and disposition: the biological fate of chemicals, 29(6), 868-876 (2001-05-17)
In a previous study, it was shown that the neurotoxic compound 1,2-diethylbenzene (1,2-DEB) is mainly hydroxylated in the alkyl chain to give 1-(2'-ethylphenyl)ethanol (1,2-EPE) and excreted in urine of rats as two glucuronide compounds (GA1 and GA2). Some findings have
François Baur et al.
Journal of medicinal chemistry, 53(9), 3675-3684 (2010-04-21)
Following a lipophilicity-based hypothesis, an 8-hydroxyquinolinone 2-aminoindan derived series of beta(2)-adrenoceptor agonists have been prepared and evaluated for their potential as inhaled ultralong-acting bronchodilators. Determination of their activities at the human beta(2)-adrenoceptor receptor showed symmetrical substitution of the 2-aminoindan moiety

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