31395
Dextran sulfate sodium salt from Leuconostoc spp.
Mr ~500,000
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About This Item
Recommended Products
biological source
(Leuconostoc spp.)
Quality Level
form
powder
mol wt
Mr ~500,000
composition
Sulfur Content, 16.0-19.0% (dry basis)
manufacturer/tradename
EDQM
useful pH range
6.0-8.0 (10 g/L)
solubility
H2O: freely soluble 50 mg/mL, clear
anion traces
chloride (Cl-): ≤100 mg/kg
cation traces
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤100 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
storage temp.
room temp
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Application
Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions. It was used for releasing DNA from DNA-histone complexes.
Biochem/physiol Actions
Dextran is a mixture of glucose polymers of varying size and geometry. Dextran in the form of dextran sulfate acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.
Preparation Note
prepared from dextran with Mr ~500,000
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Heparin and dextran sulfate antagonize PGI2 inhibition of platelet aggregation.
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Prevention of venous thromboembolism.
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A total of 28 male BALB/c mice (average weight 20.7 +/- 1.6 g) were divided into 4 treatment groups and fed a commercial diet (A), a commercial diet + induced colitis by dextran sodium sulfate (DSS) (B), Inonotus obliquus (IO)
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