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Merck
  • Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules.

Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules.

Molecular diversity (2012-05-16)
Abha Chaudhary, Pralay Das, Awanish Mishra, Pushpinder Kaur, Bikram Singh, Rajesh K Goel
要旨

A new series of benzocycloheptene amino vinyl bromide derivatives (9a-9m) were synthesized from isomeric mixture of himachalenes through two-step synthesis. The unusual structure of benzocycloheptene amino vinyl bromide derivative (9a) was confirmed by NMR and X-ray crystallography analyses. The newly synthesized amino vinyl bromide derivatives of benzocycloheptene were further evaluated for their antidepressant activities. The compound 9c had shown significant reduction in the immobility period.

材料
製品番号
ブランド
製品内容

Sigma-Aldrich
ビニルブロミド, 98%
Sigma-Aldrich
ビニルブロミド 溶液, 1.0 M in THF