InCl3-catalyzed allylic Friedel-Crafts reactions toward the stereocontrolled synthesis of 1,2,3,4-tetrahydroquinolines.

InCl3-catalyzed allylic Friedel-Crafts reactions toward the stereocontrolled synthesis of 1,2,3,4-tetrahydroquinolines.

Organic letters (2010-10-01)

David S Giera, Christoph Schneider

PMID20879793

要旨

Allyl chlorides tethered to an N-aryl moiety readily undergo InCl(3)-catalyzed Friedel-Crafts reactions to furnish highly enantiomerically enriched 1,2,3,4-tetrahydroquinolines with good yields and excellent diastereoselectivity.

材料

製品番号

ブランド

製品内容

334065

Sigma-Aldrich

塩化インジウム(III), 98%

203440

Sigma-Aldrich

塩化インジウム(III), 99.999% trace metals basis

429414

Sigma-Aldrich

塩化インジウム(III), anhydrous, powder, ≥99.999% trace metals basis