1724656

ジロートン

United States Pharmacopeia (USP) Reference Standard

• 別名: (±)-N-ヒドロキシ-N-(1-ベンゾ[b]チエン-2-イルエチル)尿素
• 実験式（ヒル表記法）: C₁₁H₁₂N₂O₂S
• CAS番号: 111406-87-2
• 分子量: 236.29
• NACRES: NA.24
• PubChem Substance ID: 329751283
• UNSPSC Code: 41116107
• MDL number: MFCD00866097

特性

• grade: pharmaceutical primary standard
• agency: USP
• API family: zileuton
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(N(O)C(N)=O)c1cc2ccccc2s1
• InChI: 1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
• InChI key: MWLSOWXNZPKENC-UHFFFAOYSA-N
• Gene Information: human ... ALOX5(240)

詳細

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Zileuton USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

ジロートンは、5-リポキシゲナーゼインヒビターです。

ジロートンは抗喘息薬の一種であり、アラキドン酸からのロイコトリエン類の生合成で初期酵素として作用する5-リポキシゲナーゼに対するインヒビターです。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

安全性情報

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361d
• pcodes: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• 保管分類: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable