おすすめの製品
product name
Discovery® C18 HPLCカラム, 5 μm particle size, L × I.D. 10 cm × 4.6 mm
物質
stainless steel column
認証
suitable for USP L1
製品種目
Discovery®
特徴
endcapped
メーカー／製品名
Discovery®
包装
1 ea of
標識化の程度
12% Carbon loading
パラメーター
≤70 °C temp. range
400 bar pressure (5801 psi)
テクニック
HPLC: suitable
LC/MS: suitable
L × 内径
10 cm × 4.6 mm
表面積
300 m2/g
表面被覆率
3 μmol/m2
不純物
<10 ppm metals
マトリックス
silica gel, high purity, spherical particle platform
fully porous particle
マトリックス活性基
C18 (octadecyl) phase
粒径
5 μm
ポアサイズ
180 Å
operating pH range
2-8
アプリケーション
food and beverages
分離法
reversed phase
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関連するカテゴリー
詳細
C18カラムを指定するあらゆる方法でDiscovery®C18カラムを使用してください。優れたピーク形状、再現性、安定性により、難しいものからルーチンまであらゆるC18カラムを用いる方法で本品を選択していただけます。
アプリケーション
- Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase.: Utilizes the Discovery® C18 HPLC Column for developing a novel enzymatic assay, aiding in malaria research and potential therapeutic target exploration (Pedro et al., 2019).
特徴および利点
- 優れた再現性
- 塩基性、酸性分析対象物に対する優れたピ-ク形状
- 安定で、低ブリ-ドのLC-MS分離
- ペプチドや小さなタンパク質の分離
- 多くの同等のC18カラムよりも低い疎水性で迅速な分析を提供
法的情報
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Choose from one of the most recent versions:
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Abbas Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(24), 2423-2429 (2011-07-26)
A novel isocratic reversed-phase high performance liquid-chromatography/ultraviolet detection method for simultaneous determination of cefdinir and cefixime in human plasma was developed and validated after optimization of various chromatographic conditions and other experimental parameters. Sample preparation based on a simple extraction
Himal Paudel Chhetri et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 22(5), 483-487 (2014-12-05)
This study presents the optimization of a simple HPLC-UV method for the determination of metformin in human plasma. Ion pair separation followed by UV detection was performed on deproteinized human plasma samples. The separation was carried out on a Discovery
Ramisetti Nageswara Rao et al.
Journal of separation science, 32(9), 1312-1322 (2009-04-29)
Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions indispensable for identification of the structures were
Sheelendra Pratap Singh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(27), 2845-2851 (2011-09-06)
Tamoxifen is the agent of choice for the treatment of estrogen receptor-positive breast cancer. Tamoxifen is a substrate of P-glycoprotein (P-gp) and microsomal cytochrome P450 (CYP) 3A, and biochanin A (BCA) is an inhibitor of P-gp and CYP3A. Hence, it
関連コンテンツ
Discovery C18 and C8 HPLC Columns products offered
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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