T6950

チザニジン 塩酸塩

≥98% (HPLC), powder

• 別名: 5-クロロ-N-(4,5-ジヒドロ-1H-イミダゾール-2-イル)-2,1,3-ベンゾチアゾール-4-アミン 塩酸塩
• 実験式（ヒル表記法）: C₉H₉Cl₂N₅S
• CAS番号: 64461-82-1
• 分子量: 290.17
• MDL番号: MFCD00798231
• UNSPSCコード: 12352200
• PubChem Substance ID: 24724634
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• 色: white
• 溶解性: H₂O: >20 mg/mL
• オーガナイザー: Acorda Therapeutics
• SMILES記法: Cl[H].Clc1ccc2nsnc2c1NC3=NCCN3
• InChI: 1S/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
• InChI Key: ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
• 遺伝子情報: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

詳細

アプリケーション

Tizanidine hydrochloride has been used for developing spectrophotometric methods for the validation of skeletal muscle relaxants.

生物化学的／生理学的作用

Tizanidine hydrochloride is known to function as a skeletal muscle relaxant that acts centrally. Furthermore, this relaxant functions at spinal and supraspinal levels to block excitatory interneurons. This drug is used for the symptomatic relief of spasticity and painful muscle spasms.

α₂-adrenoceptor agonist.

特徴および利点

This compound was developed by Acorda Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

調製ノート

Tizanidine hydrochloride is soluble in water at a concentration that is greater than 20 mg/ml.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves