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About This Item
実験式（ヒル表記法）:
C41H67NO15
CAS番号:
分子量:
813.97
Beilstein:
1418238
EC Number:
MDL番号:
UNSPSCコード:
51101500
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![(3R,5R,6S,7R,14S)-12-[(2,6-DIDEOXY-3-O-METHYL-ALPHA-L-GLYCERO-HEXOPYRANOSYL)OXY]-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-1,9-DIOXASPIRO[2.13]HEXADEC-14-YL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-D-GLYCERO-HEXOPYRANOSIDE AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/173/328/834e3009-73db-49dd-86d3-42170cf81f5a/640/834e3009-73db-49dd-86d3-42170cf81f5a.png)
作用機序
enzyme | inhibits
protein synthesis | interferes
SMILES記法
CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1OC(C)=O)O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3OC(C)=O)N(C)C)[C@@H](C)C[C@@]4(CO4)C(=O)[C@H](C)[C@@H](OC(C)=O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C
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詳細
Chemical structure: macrolide
保管分類コード
13 - Non Combustible Solids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Y-F Cao et al.
Xenobiotica; the fate of foreign compounds in biological systems, 40(1), 38-47 (2009-12-17)
Schizandrin is recognized as the major absorbed effective constituent of Fructus schisandrae, which is extensively applied in Chinese medicinal formula. The present study aimed to profile the phase I metabolites of schizandrin and identify the cytochrome P450 (CYP) isoforms involved.
Yu Liu et al.
Comparative medicine, 58(6), 580-587 (2009-01-20)
The objective of this study was to demonstrate that Bama miniature pigs are a suitable experimental animal model for the evaluation of drugs for man. To this end, in vitro lovastatin metabolism at the minipig liver microsomal level and in
Y H Choi et al.
British journal of pharmacology, 149(4), 424-430 (2006-08-31)
The types of hepatic microsomal cytochrome P450 (CYP) isozymes responsible for the metabolism of metformin in humans and rats have not been published to date. Therefore, a series of experiments using various inducers and inhibitors of CYP isozymes was conducted
Soo H Bae et al.
The Journal of pharmacy and pharmacology, 61(12), 1637-1642 (2009-12-05)
It has been reported that hepatic cytochrome P450 (CYP)2C9 and CYP3A4 are responsible for the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in humans. However, in-vivo studies in rats have not been reported. Sildenafil (20 mg/kg) was administered
Güliz Gürel et al.
Antimicrobial agents and chemotherapy, 53(12), 5010-5014 (2009-09-10)
Structures have been obtained for the complexes that triacetyloleandomycin and mycalamide A form with the large ribosomal subunit of Haloarcula marismortui. Triacetyloleandomycin binds in the nascent peptide tunnel and inhibits the activity of ribosomes by blocking the growth of the
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