SAB5702162

Anti-Serotonin transporter Antibody, clone 5T7M2, Rabbit Monoclonal

• 別名: 5-HTT,5-HTTLPR,5HTT,HTT,OCD1,SERT,SERT1,hSERT,SLC6A4
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 5T7M2, monoclonal
• 形状: liquid
• 分子量: 70 kDa
• 化学種の反応性: human, rat
• 濃度: 0.25 mg/mL
• テクニック: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:1000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLG
• UniProtアクセッション番号: P31645
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SLC6A4(6532)

詳細

詳細

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Serotonin transporter (P31645).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IF/ICC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1