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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 87 kDa
化学種の反応性
mouse, human
濃度
~1 mg/mL
テクニック
ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TACC1(6867)
詳細
Anti-TACC1 Antibody detects endogenous levels of total TACC1 protein.
The gene TACC1 (transforming acidic coiled-coil containing protein 1) is mapped to human chromosome 8p11. It is highly expressed during embryogenesis and is weakly expressed in differentiated tissues. TACC1 belongs to the TACC family of proteins and localizes in the nucleus.
The gene TACC1 (transforming acidic coiled-coil containing protein 1) is mapped to human chromosome 8p11. It is highly expressed during embryogenesis and is weakly expressed in differentiated tissues. TACC1 belongs to the TACC family of proteins and localizes in the nucleus.
免疫原
The antiserum was produced against synthesized peptide derived from human TACC1.
Immunogen Range: 11-60
Immunogen Range: 11-60
生物化学的／生理学的作用
TACC1 (transforming acidic coiled-coil containing protein 1) participates in the transcriptional regulation of nuclear hormone receptors (NRs). It is associated with breast and ovarian cancers and leukemia.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Omkaram Gangisetty et al.
Oncogene, 23(14), 2559-2563 (2004-02-10)
Dysregulation of the human transforming acidic coiled coil (TACC) genes is thought to be important in the development of multiple myeloma, breast and gastric cancer. However, even though these proteins have been implicated in the control of cell growth and
Aiping Ding et al.
PloS one, 8(12), e82136-e82136 (2013-12-21)
NPM, TFF3 and TACC1 are molecular markers that play important roles in cell differentiation. Herein, we investigated their prognostic impact in patients with primary gastric cancer (GC) and determined whether they could be used as markers of more aggressive gastric
Romain Guyot et al.
BMC molecular biology, 11, 3-3 (2010-01-19)
The transcriptional activity of Nuclear hormone Receptors (NRs) is regulated by interaction with coactivator or corepressor proteins. Many of these cofactors have been shown to have a misregulated expression or to show a subcellular mislocalization in cancer cell lines or
Jonathan J Wilde et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(10), 2565-2579 (2017-02-06)
Diencephalic defects underlie an array of neurological diseases. Previous studies have suggested that retinoic acid (RA) signaling is involved in diencephalic development at late stages of embryonic development, but its roles and mechanisms of action during early neural development are
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