SAB4502184

Anti-Progesterone Receptor antibody produced in rabbit

affinity isolated antibody

• 別名: NR3C3, PGR, PR, PRGR, nuclear receptor 3C3
• MDL番号: MFCD00239723
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 98 kDa
• 化学種の反応性: rat, mouse, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:5000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• NCBIアクセッション番号: P06401
• UniProtアクセッション番号: P06401
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PGR(5241)

詳細

詳細

Anti-Progesterone receptor antibody detects endogenous levels of total progesterone receptor protein.

The progesterone receptor (PR) gene is mapped to human chromosome 11q22–23. The gene encodes for two isoforms, namely PR-A and PR-B, each of which is transcribed from a specific promoter region. The encoded receptor belongs to the family of steroid hormone receptors.

免疫原

The antiserum was produced against synthesized peptide derived from human Progesterone Receptor.

Immunogen Range: 261-310

アプリケーション

Anti-Progesterone receptor antibody produced in rabbit has been used in western blotting and immunohistochemistry.

生物化学的／生理学的作用

Progesterone receptor (PR) mediates the actions of progesterone which is essential to maintain pregnancy. PR is known to regulate the genes involved in the process of cell cycle, cell adhesion, invasion, differentiation, proliferation, inflammation, and apoptosis. PR expression might serve as a biomarker in axillary lymph node (ALN) metastasis. Abnormal expression of PR is observed in breast cancer.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable