SAB4501939

Anti-B-MYB antibody produced in rabbit

affinity isolated antibody

• 別名: BMYB, MYBB, MYBL2, Myb-related protein B
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 79 kDa
• 化学種の反応性: mouse, human, rat
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBIアクセッション番号: P10244
• UniProtアクセッション番号: P10244
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MYBL2(4605)

詳細

詳細

MYB proto-oncogene like 2/v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2/B-MYB) belongs to the MYB family of transcription factors. MYBL2 gene is located on human chromosome 20q13.

免疫原

The antiserum was produced against synthesized peptide derived from human B-Myb.

Immunogen Range: 551-600

生物化学的／生理学的作用

MYB proto-oncogene like 2/v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2/B-MYB) protein regulates cell proliferation, differentiation, and DNA repair. It participates in DNA replication in embryonic stem cells. MYBL2 protein can modulate stem cell genes. MYBL2 gene expression is altered in breast, ovarian, liver, colon, rectal, blood, brain, and bladder cancers. MYBL2 affects cell cycle progression and apoptosis in a regulated manner. It serves as a cell cycle modulator in hepatocellular carcinoma (HCC).

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable