コンテンツへスキップ
Merck

SAB4501294

Sigma-Aldrich

Anti-GLUR1 antibody produced in rabbit

affinity isolated antibody

別名:

GluR-1, GluR-A, GluR-K1, Glutamate receptor 1, Glutamate receptor ionotropic

ログイン組織・契約価格を表示する


About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

antigen 101 kDa

化学種の反応性

human, mouse, rat

濃度

~1 mg/mL

テクニック

ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... GRIA1(2890)

詳細

Anti-GLUR1 Antibody detects endogenous levels of total GLUR1 protein.
The gene encoding GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is localized on human chromosome 5q33.2. It is expressed mainly in the brain. GLUR1 is a glutamate receptor subunit, which forms a glutamate-gated ion channel. It is part of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor family.

免疫原

The antiserum was produced against synthesized peptide derived from human GluR1.

Immunogen Range: 829-878

生物化学的/生理学的作用

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It has been associated with migraine.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our 製品選択ツール.

保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Postsynaptic glutamate receptor δ family contributes to presynaptic terminal differentiation and establishment of synaptic transmission
Kuroyanagi T, et al.
Proceedings of the National Academy of Sciences of the USA, 106(12), 4912-4916 (2009)
Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility
Formicola D, et al.
BMC Medical Genetics, 11(1), 103-103 (2010)
Functional organization of the GluR1 glutamate receptor promoter
Borges K and Dingledine R
The Journal of Biological Chemistry, 276(28), 25929-25938 (2001)
Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice
Mead AN and Stephens DN
The Journal of Neuroscience, 23(3), 1041-1048 (2003)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)