R4155

Anti-hnRNP-E1/E2 (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: Anti-HNRPE1/HNRPE2, Anti-Heterogeneous nuclear ribonucleoprotein E1/E2, Anti-PCBP1/PCBP2, Anti-poly(rC) binding protein 1 /protein 2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~37 kDa
• 化学種の反応性: human, rat, mouse
• 包装: antibody small pack of 25 μL
• 濃度: ~1.0 mg/mL
• テクニック: immunoprecipitation (IP): 5-10 μg using K562 cell extract; western blot: 0.5-1 μg/mL using K562 cell extract
• UniProtアクセッション番号: Q15365
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PCBP1(5093) ; mouse ... Pcbp1(23983) ; rat ... Pcbp1(500242)

詳細

詳細

hnRNP-E1/E2 (heterogeneous nuclear ribonucleoproteins) belongs to hnRNP (heterogeneous ribonucleoprotein) family. It is also known as poly-C binding proteins (PCBP) 1 and 2. It is located on chromosome 2p13. PCBP1 gene has no intron and codes for a 356 amino acid poly (rC) binding protein 1, that is of 35kDa. It has three K-Homology (KH) domains and two nuclear localization signals.

アプリケーション

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

生物化学的／生理学的作用

hnRNP-E1/E2 (heterogeneous nuclear ribonucleoproteins) participates in the development and progression of tumor. It is involved in several transcriptional and posttranscriptional events like mRNA transcription regulation, transportation, splicing, translation, and stabilization. It plays critical roles in cancer apoptosis, metastasis, invasion and malignant transformation. It may also participates in epithelial-mesenchymal transition (EMT).

物理的形状

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)