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品質水準
形状
liquid
濃度
10 ng/μL
テクニック
DNA extraction: suitable
DNA sequencing: suitable
PCR: suitable
輸送温度
ambient
保管温度
−20°C
詳細
Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses.1 Prophyromonas gingivalis genomic DNA microbial standard can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs.
Porphyromonas gingivalis, is a gram negative bacterium which is an etiologic agent of adult periodontitis, a chronic inflammatory disease characterized by the destruction of the supportive tissue surrounding teeth. Studies have shown that LPS from P. gingivalis plays an important role in this disease. 2-5 The association of the oral microbiota, including P. gingivalis, with various pathological states has been reported. These include development of Alzheimer′s disease6, role in oral cancers7, preterm birth8 and rheumatoid arthritis.9
Read here how to use our standards to ensure data integrity for your microbiome research.
アプリケーション
Suitable for Quantitative standard for PCR, Sequencing and NGS
特徴および利点
- Individual microbial standard for microbiomics and meta-genomics workflow
- Suitable standard for PCR, sequencing and NGS
- Improve Bioinformatics analyses
- Increases reproducibility
- Compare results lab to lab
物理的形状
The genomic DNA is provided at ≥10 ng/μl concentration in TE buffer pH 8.0.
その他情報
It is recommended to avoid freeze thaw cycles of this product.
保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MBD0004-300NG-KC:
MBD0004-0.3UG-PW-P:
MBD0004-VAR:
MBD0004-0.3UG-PW:
MBD0004-0.3UG:
MBD0004-0.3UG-KC:
MBD0004-BULK:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Zijian Cheng et al.
Best practice & research. Clinical rheumatology, 31(1), 19-30 (2017-12-10)
There is an epidemiological association between periodontitis and rheumatoid arthritis (RA), which is hypothesised to lead to enhanced generation of RA-related autoantibodies that can be detected years before the onset of RA symptoms. Periodontitis is a common dysbiotic disease; tissue
Alice Harding et al.
Frontiers in aging neuroscience, 9, 398-398 (2017-12-19)
Longitudinal monitoring of patients suggests a causal link between chronic periodontitis and the development of Alzheimer's disease (AD). However, the explanation of how periodontitis can lead to dementia remains unclear. A working hypothesis links extrinsic inflammation as a secondary cause
Virulence factors of Porphyromonas gingivalis.
S C Holt et al.
Periodontology 2000, 20, 168-238 (1999-10-16)
Pourya Gholizadeh et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 552-558 (2016-10-04)
The oral cavity is inhibited by many of the bacterial species. Some of them have a key role in the development of oral disease. Interrelationships between oral microbiome and systemic conditions such as head-and-neck cancer have become increasingly appreciated in
Charles M Cobb et al.
International journal of women's health, 9, 551-559 (2017-08-30)
Significant evidence supports an association between periodontal pathogenic bacteria and preterm birth and preeclampsia. The virulence properties assigned to specific oral pathogenic bacteria, for example, Fusobacterium nucleatum, Porphyromonas gingivalis, Filifactor alocis, Campylobacter rectus, and others, render them as potential collaborators
資料
DNA standards enhance metagenomics research integrity, offering precise species study and mixed community standards.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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