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主要文書

原産地証明書（COO）/試験成績書（COA）

EHU135251

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human HIPK2

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About This Item

UNSPSCコード:

41105324

NACRES:

NA.51

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Sigma-Aldrich

EHU133631

MISSION^® esiRNA

Sigma-Aldrich

SAB2500328

抗DPP4/CD26 ヤギ宿主抗体

Sigma-Aldrich

804568

(R,S)-Bode Kinetic Resolution Catalyst

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168440

α,β-ジブロモヒドロケイ皮酸

Sigma-Aldrich

8.02824

Cyclohexene

Sigma-Aldrich

ECM104

Millicoat^® Human Collagen Type I Coated Strips (96-Wells)

SIRNA

MISSION^® siRNA Product Offerings

Sigma-Aldrich

SAB2100069

抗AFF3抗体ウサギ宿主抗体

Sigma-Aldrich

HPA015794

Anti-PKD2 antibody produced in rabbit

Sigma-Aldrich

HPA066490

Anti-PMS2 antibody produced in rabbit

詳細

品質水準

100

製品種目

MISSION^®

フォーム

lyophilized powder

esiRNA cDNA標的配列

TTGGCCGTTATATCCAGGAGCTTCGGAGTATGATCAGATTCGGTATATTTCACAAACACAGGGTTTGCCTGCTGAATATTTATTAAGCGCCGGGACAAAGACAACTAGGTTTTTCAACCGTGACACGGACTCACCATATCCTTTGTGGAGACTGAAGACACCAGATGACCATGAAGCAGAGACAGGGATTAAGTCAAAAGAAGCAAGAAAGTACATTTTCAACTGTTTAGATGATATGGCCCAGGTGAACATGACGACAGATTTGGAAGGGAGCGACATGTTGGTAGAAAAGGCTGACCGGCGGGAGTTCATTGACCTGTTGAAGAAGATGCTGACCATTGATGCTGACAAGAGAATCACTCCAATCGAAACCCTGAACCATCCCTTTGTCACCATGACACACTTACTCGATTTTCCCCACAGC

Ensembl |ヒトアクセッション番号

ENSG00000064393

NCBIアクセッション番号

NM_001113239

輸送温度

ambient

保管温度

−20°C

遺伝子情報

human ... HIPK2(28996) , HIPK2(28996)

詳細

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法的情報

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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Role of Homeodomain-Interacting Protein Kinase 2 in the Pathogenesis of Tissue Fibrosis in Keloid-Derived Keratinocytes.

Yi-Xuan Zhao et al.

Annals of plastic surgery, 79(6), 546-551 (2017-10-21)

Epithelial-mesenchymal transition (EMT) plays a critical role in fibrotic keloid formation, which is characterized by excessive collagen and extracellular matrix synthesis and deposition. Growing evidence suggests that the serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) acts upstream of several major

HIPK2 overexpression relieves hypoxia/reoxygenation-induced apoptosis and oxidative damage of cardiomyocytes through enhancement of the Nrf2/ARE signaling pathway.

Xiaoyan Dang et al.

Chemico-biological interactions, 316, 108922-108922 (2019-12-15)

Homeodomain interacting protein kinase-2 (HIPK2) has emerged as a crucial stress-responsive kinase that plays a critical role in regulating cell survival and apoptosis. However, whether HIPK2 participates in regulating cardiomyocyte survival during myocardial ischemia/reperfusion injury remains unclear. Here, we investigated

CircRNA-016901 silencing attenuates irradiation-induced injury in bone mesenchymal stem cells via regulating the miR-1249-5p/HIPK2 axis.

Xianhui Wen et al.

Experimental and therapeutic medicine, 21(4), 355-355 (2021-03-19)

Currently, bone marrow transplantation remains the basic treatment for various hematological tumors and irradiation is one of the most important pretreatment methods. However, irradiation pretreatment may result in damage to bone mesenchymal stem cells (BMSCs). The present study aimed to

Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy.

Zhengyu Jiang et al.

Cell death & disease, 9(9), 847-847 (2018-08-30)

Sepsis is the leading cause of death in intensive care units worldwide. Autophagy has recently been shown to protect against sepsis-induced liver injury. Here, we investigated the roles of homeodomain-interacting protein kinase 2 (HIPK2) in the molecular mechanism of sepsis-induced

EGFR drives the progression of AKI to CKD through HIPK2 overexpression.

Luyang Xu et al.

Theranostics, 9(9), 2712-2726 (2019-05-28)

The molecular mechanism underlying the transition of acute kidney injury (AKI) to chronic kidney disease (CKD) induced by vancomycin (VAN) remains largely unknown. Methods: The mice model of VAN drives AKI to CKD was developed to investigate the role and

主要文書

MISSION^® esiRNA