すべての画像(1)

資料

原産地証明書（COO）/試験成績書（COA）

EHU086621

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human TLR4

ログイン組織・契約価格を表示する

すべての画像(1)

About This Item

UNSPSCコード:

41105324

NACRES:

NA.51

おすすめの製品

Slide 1 of 10

1 of 10

Sigma-Aldrich

SIC001

MISSION^® siRNA Universal Negative Control #1

Sigma-Aldrich

S1452

MISSION^® siRNAトランスフェクション試薬

SIRNA

MISSION^® siRNA Product Offerings

Sigma-Aldrich

EHU019931

MISSION^® esiRNA

Sigma-Aldrich

EHU081921

MISSION^® esiRNA

Sigma-Aldrich

EHU065921

MISSION^® esiRNA

Sigma-Aldrich

EHUEGFP

MISSION^® esiRNA

Sigma-Aldrich

EHU019541

MISSION^® esiRNA

GF49140075

Polyethylene - High Density

MIRNA

MISSION^® miRNA Product Offerings

詳細

製品種目

MISSION^®

形状

lyophilized powder

esiRNA cDNA標的配列

CAACAAAGGTGGGAATGCTTTTTCAGAAGTTGATCTACCAAGCCTTGAGTTTCTAGATCTCAGTAGAAATGGCTTGAGTTTCAAAGGTTGCTGTTCTCAAAGTGATTTTGGGACAACCAGCCTAAAGTATTTAGATCTGAGCTTCAATGGTGTTATTACCATGAGTTCAAACTTCTTGGGCTTAGAACAACTAGAACATCTGGATTTCCAGCATTCCAATTTGAAACAAATGAGTGAGTTTTCAGTATTCCTATCACTCAGAAACCTCATTTACCTTGACATTTCTCATACTCACACCAGAGTTGCTTTCAATGGCATCTTCAATGGCTTGTCCAGTCTCGAAGTCTTGAAAATGGCTGGCAATTCTTTCCAGGAAAACTTCCTTCCAGATATCTTCACAGAGCTGAGAAACTTGACCTTCCTGGACCTCTC

Ensembl |ヒトアクセッション番号

ENSG00000136869

NCBIアクセッション番号

NM_138554

輸送温度

ambient

保管温度

−20°C

遺伝子情報

human ... TLR4(7099) , TLR4(7099)

詳細

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法的情報

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA）を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

High Phosphate-Induced Calcification of Vascular Smooth Muscle Cells is Associated with the TLR4/NF-κb Signaling Pathway.

Daohai Zhang et al.

Kidney & blood pressure research, 42(6), 1205-1215 (2017-12-12)

Hyperphosphatemia is one of the most notable features of chronic kidney disease (CKD). Numerous epidemiological and clinical studies have found that high serum phosphate concentrations are associated with calcification in the coronary arteries. However, the mechanisms underlying the vascular calcification

Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA.

Emmeline L Blanchard et al.

Molecular therapy. Nucleic acids, 14, 52-66 (2018-12-24)

The characterization of innate immune activation is crucial for vaccine and therapeutic development, including RNA-based vaccines, a promising approach. Current measurement methods quantify type I interferon and inflammatory cytokine production, but they do not allow for the isolation of individual pathways, do

Toll-like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease.

Daniela Verzola et al.

Journal of cachexia, sarcopenia and muscle, 8(1), 131-144 (2016-11-30)

Inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia but why uremia up-regulates pro-inflammatory cytokines is unknown. Toll-like receptors (TLRs) regulate locally the innate immune responses, but it is unknown whether in chronic kidney disease

Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm.

Chao-Han Lai et al.

PloS one, 11(1), e0146565-e0146565 (2016-01-08)

Toll-like receptor (TLR) family plays a key role in innate immunity and various inflammatory responses. TLR4, one of the well-characterized pattern-recognition receptors, can be activated by endogenous damage-associated molecular pattern molecules such as high mobility group box 1 (HMGB1) to

Unfractionated Heparin Alleviates Human Lung Endothelial Barrier Dysfunction Induced by High Mobility Group Box 1 Through Regulation of P38-GSK3β-Snail Signaling Pathway.

Zhenggang Luan et al.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 46(5), 1907-1918 (2018-05-03)

The high mobility group box 1 (HMGB1) has been regarded as an important inflammatory mediator. Previous studies showed the involvement of HMGB1 protein in the dysfunction of endothelial barrier function during acute lung injury. However, the molecular mechanism remains unclear.

資料

MISSION^® esiRNA