D6035

ジソピラミド リン酸塩

• 別名: α-ジイソプロピルアミノエチル-α-フェニルピリジン-2-アセトアミド
• 化学式: C₂₁H₂₉N₃O · H₃PO₄
• CAS番号: 22059-60-5
• 分子量: 437.47
• NACRES: NA.77
• PubChem Substance ID: 24277706
• UNSPSC Code: 12352200
• EC Number: 244-756-1
• MDL number: MFCD00069254
• Form: solid

特性

• form: solid
• Quality Segment: 200
• SMILES string: OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C
• InChI: 1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)
• InChI key: CGDDQFMPGMYYQP-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

詳細

Application

Disopyramide phosphate salt has been used as an internal standard for plasma sample analysis by mass spectrometry.[1] It might be used as a test compound in a teratogenicity study.[2]

Biochem/physiol Actions

Disopyramide is found to stabilize the cell membrane by altering the action potential. It might act as an antiarrhythmic agent.

クラスIA抗不整脈薬であり、ナトリウムチャネルブロッカ-です。

安全性情報

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• 保管分類: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves